{"entity":{"id":"nct07309289","kind":"trial","name":"NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer","aka":[],"tldr":"A phase 3 trial in colorectal cancer, run by Shanghai Zhongshan Hospital, now recruiting.","summary":"NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer is a phase 3, randomised interventional study registered as NCT07309289 by Shanghai Zhongshan Hospital, with a registry enrolment figure of 144 participants, started 2025-07-01 and due to reach its primary completion in 2029-03-01. Interventions recorded: NALIRIFOX plus targeted therapy; FOLFOX plus targeted therapy. Conditions listed: Metastatic Colorectal Cancer (CRC). Primary outcome: 18 month PFS rate. Colorectal eligibility wording from the registry: \"* Histopathologically confirmed patient with an inoperable metastatic colorectal adenocarcinoma\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07309289","url":"https://clinicaltrials.gov/study/NCT07309289"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07309289","phase":"3","setting":"NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer: a Multicentre, Open-label, Randomised Trial","sponsor":"Shanghai Zhongshan Hospital","enrolled":144,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07309289/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}