{"entity":{"id":"nct07337551","kind":"trial","name":"Gossypol Acetate + FOLFIRI + Bev in mCRC With TP53-Mutant and LRPPRC Positive","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Guiying Wang, not yet recruiting.","summary":"Gossypol Acetate + FOLFIRI + Bev in mCRC With TP53-Mutant and LRPPRC Positive is a phase 2, interventional study registered as NCT07337551 by Guiying Wang, with a registry enrolment figure of 20 participants, started 2026-02-01 and due to reach its primary completion in 2028-02-01. Interventions recorded: Gossypol acetate Combined with Bevacizumab and FOLFIRI. Conditions listed: Patients With Metastatic Colorectal Cancer Who Were TP53-mutant and LRPPRC-positive and Had Previously Failed Prior First-line Treatment. Primary outcome: Primary Endpoint. Colorectal eligibility wording from the registry: \"Histopathologically or cytologically confirmed adenocarcinoma of the colon or rectum\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07337551","url":"https://clinicaltrials.gov/study/NCT07337551"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07337551","phase":"2","setting":"Gossypol Acetate Combined With Bevacizumab and FOLFIRI as Second-Line Therapy for Metastatic Colorectal Cancer With TP53 Mutation and LRPPRC Positivity: A Single-Center, Single-Arm Clinical Study","sponsor":"Guiying Wang","enrolled":20,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07337551/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}