{"entity":{"id":"nct07369505","kind":"trial","name":"Sapu003 in Advanced mTOR-sensitive Solid Tumors","aka":[],"tldr":"A phase 1 trial of Sapu003 (SAPU-003, everolimus Deciparticle) run by SAPU NANO (US) LLC, now recruiting.","summary":"Sapu003 in Advanced mTOR-sensitive Solid Tumors is a phase 1 interventional study registered as NCT07369505 by SAPU NANO (US) LLC, with 27 participants planned, started 2025-12-15. Conditions recorded: Breast Cancer Metastatic, Renal Cell Carcinoma (RCC), Neuroendocrine Tumors, Tuberous Sclerosis Complex (TSC) and Hepatocellular Carcinoma (HCC). Interventions recorded: Sapu003 and Exemestane 25 MG.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07369505","url":"https://clinicaltrials.gov/study/NCT07369505"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","rcc","neuroendocrine","hcc","breast-hr-positive"],"sections":[],"technologies":[],"targets":[],"drugs":["sapu-003"],"companies":["sapu-nano"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07369505","phase":"1","setting":"A Phase 1b, Open-Label, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics of Sapu003 in Advanced mTOR-sensitive Solid Tumors (With or Without Exemestane)","sponsor":"SAPU NANO (US) LLC","enrolled":27,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07369505/","neighbours":{"cancer":[{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"neuroendocrine","kind":"cancer","name":"Neuroendocrine tumours","route":"/cancers/neuroendocrine/"},{"id":"rcc","kind":"cancer","name":"Renal cell carcinoma","route":"/cancers/rcc/"}],"drug":[{"id":"sapu-003","kind":"drug","name":"Sapu003 (SAPU-003, everolimus Deciparticle)","route":"/drugs/sapu-003/"}],"company":[{"id":"sapu-nano","kind":"company","name":"Sapu Nano","route":"/companies/sapu-nano/"}]}}