{"entity":{"id":"nct07378306","kind":"trial","name":"FMD and Neoadjuvant Chemo-immunotherapy in TNBC","aka":["FACT-TN"],"tldr":"A phase 2 trial of toripalimab in triple-negative breast cancer, run by Sun Yat-sen University, now recruiting.","summary":"FMD and Neoadjuvant Chemo-immunotherapy in TNBC is a phase 2, interventional study registered as NCT07378306 by Sun Yat-sen University, with a registry enrolment figure of 80 participants, started 2026-03-05 and due to reach its primary completion in 2029-06-30. Interventions recorded: Fasting-mimicking diet; Chemotherapy; Toripalimab. Conditions listed: Breast Cancer. Triple-negative eligibility wording from the registry: \"* Triple-negative or near-triple-negative subtype, defined as HR-negative or low expression (ER and/or PR positivity rate 1%-10%) and HER2-negative (IHC 0, 1+, or 2+ with FISH-negative)\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07378306","url":"https://clinicaltrials.gov/study/NCT07378306"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["toripalimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07378306","phase":"2","setting":"FAsting-mimicking Diet in Combination With Neoadjuvant Chemo-immunoTherapy for Early or Locally Advanced Triple-Negative Breast Cancer: the Prospective, Single-arm, Open-lable, Phase 2 FACT-TN Trial","sponsor":"Sun Yat-sen University","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07378306/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"toripalimab","kind":"drug","name":"Toripalimab","route":"/drugs/toripalimab/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}