{"entity":{"id":"nct07394192","kind":"trial","name":"Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer","aka":["PKUCH- R11"],"tldr":"A phase 2 trial in colorectal cancer, run by Peking University Cancer Hospital & Institute, not yet recruiting.","summary":"Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer is a phase 2, interventional study registered as NCT07394192 by Peking University Cancer Hospital & Institute, with a registry enrolment figure of 44 participants, started 2026-02-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: short-course radiotherapy that preserves tumor-draining lymph nodes. Conditions listed: Rectal Cancer; Radiotherapy; PD-1 Inhibitor. Primary outcome: pathologic complete response rate. Colorectal eligibility wording from the registry: \"* Fibrocolonoscopy or digital rectal examination indicates that the distal border of the lesion is located 5-10 cm from the anal verge\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07394192","url":"https://clinicaltrials.gov/study/NCT07394192"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07394192","phase":"2","setting":"Exploratory Study on the Efficacy and Safety of Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer","sponsor":"Peking University Cancer Hospital & Institute","enrolled":44,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07394192/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}