{"entity":{"id":"nct07405736","kind":"trial","name":"Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.","summary":"Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07405736 by Sun Yat-sen University, with a registry enrolment figure of 124 participants, started 2026-02-24 and due to reach its primary completion in 2027-06-01. Interventions recorded: maintenance therapy plus lubiprostone; maintenance therapy. Conditions listed: Colorectal Cancer Metastatic; Peritoneal (Metastatic) Cancer; Peritoneal Metastasis; Colorectal Cancer (CRC); MSS Metastatic Colorectal Cancer. Primary outcome: 1-year Progression-Free Survival (PFS) Rate. Colorectal eligibility wording from the registry: \"* Histologically confirmed colon/rectal adenocarcinoma with molecular status confirmed as pMMR or MSS\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07405736","url":"https://clinicaltrials.gov/study/NCT07405736"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07405736","phase":"2","setting":"Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer, A Randomized Controlled Phase II Study","sponsor":"Sun Yat-sen University","enrolled":124,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07405736/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}