{"entity":{"id":"nct07409844","kind":"trial","name":"Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer","aka":["RESET C2"],"tldr":"A phase 2 trial in colorectal cancer, run by Ismail Gögenur, not yet recruiting.","summary":"Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer is a phase 2, interventional study registered as NCT07409844 by Ismail Gögenur, with a registry enrolment figure of 152 participants, started 2026-03-01 and due to reach its primary completion in 2028-03-01. Interventions recorded: 1 Cycle of Pembrolizumab; 2 Cycles of Pembrolizumab; 3 Cycles of Pembrolizumab; Additional Cycle of Pembrolizumab. Conditions listed: DMMR Colorectal Cancer; Colon Cancer Stage I; Colon Cancer Stage II/III; Pembrolizumab; Immunotherapy. Primary outcome: Proportion of patients with clinical complete response (cCR). Colorectal eligibility wording from the registry: \"Clinical UICC stage I-III dMMR colon carcinoma\". Sites: Denmark. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07409844","url":"https://clinicaltrials.gov/study/NCT07409844"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer","msi-high-colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07409844","phase":"2","setting":"Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer: A National, Multicentre, Personalised, Phase II Study (RESET C2)","sponsor":"Ismail Gögenur","enrolled":152,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07409844/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"msi-high-colorectal","kind":"cancer","name":"Mismatch-repair deficient (MSI-high) colorectal cancer","route":"/cancers/msi-high-colorectal/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}