{"entity":{"id":"nct07414927","kind":"trial","name":"A Clinical Study for the Efficacy and Safety of BL0020 Injection in Patients With Small Cell Lung Cancer Transformed From Non-Small Cell Lung Cancer Following E","aka":[],"tldr":"A phase 1/2 trial in lung cancer, run by Shanghai Best-Link Bioscience, LLC, not yet recruiting.","summary":"A Clinical Study for the Efficacy and Safety of BL0020 Injection in Patients With Small Cell Lung Cancer Transformed From Non-Small Cell Lung Cancer Following EGFR TKI Therapy is a phase 1/2, interventional study registered as NCT07414927 by Shanghai Best-Link Bioscience, LLC, with a registry enrolment figure of 48 participants, started 2026-03-27 and due to reach its primary completion in 2027-12-22. Interventions recorded: BL0020. Conditions listed: Small Cell Carcinoma of Lung. Primary outcome: Objective response rate (ORR). Lung eligibility wording from the registry: \"Patients with initial diagnosis of EGFR-mutated NSCLC and histologically or cytologically confirmed transformation to SCLC following treatment with EGFR tyrosine kinase inhibitor\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07414927","url":"https://clinicaltrials.gov/study/NCT07414927"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["sclc","egfr-mutant-nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07414927","phase":"1/2","setting":"An Open-Label, Single-Arm Phase I/II Clinical Study to Evaluate the Efficacy and Safety of BL0020 Injection in Patients With Small Cell Lung Cancer Transformed From Non-Small Cell Lung Cancer Following EGFR TKI Therapy","sponsor":"Shanghai Best-Link Bioscience, LLC","enrolled":48,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07414927/","neighbours":{"cancer":[{"id":"egfr-mutant-nsclc","kind":"cancer","name":"EGFR-mutated non-small-cell lung cancer","route":"/cancers/egfr-mutant-nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}