{"entity":{"id":"nct07435038","kind":"trial","name":"Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS","aka":[],"tldr":"A phase 1/2 trial in pancreatic cancer, run by Betta Pharmaceuticals Co., Ltd., now recruiting.","summary":"Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS is a phase 1/2, interventional study registered as NCT07435038 by Betta Pharmaceuticals Co., Ltd., with a registry enrolment figure of 120 participants, started 2026-01-29 and due to reach its primary completion in 2028-12-28. Interventions recorded: BPI-572270. Conditions listed: Non-small Cell Lung Cancer (NSCLC); Colorectal Cancer (CRC); Pancreatic Ductal Adenocarcinoma (PDAC); Advanced Solid Tumors. Primary outcome: DLT; RP2D; ORR. Sites: Australia, China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07435038","url":"https://clinicaltrials.gov/study/NCT07435038"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07435038","phase":"1/2","setting":"A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS.","sponsor":"Betta Pharmaceuticals Co., Ltd.","enrolled":120,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07435038/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}