{"entity":{"id":"nct07444606","kind":"trial","name":"Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases","aka":[],"tldr":"A phase 1 trial of DNX-2401 run by M.D. Anderson Cancer Center, now recruiting.","summary":"Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases is a phase 1 interventional study registered as NCT07444606 by M.D. Anderson Cancer Center, with 50 participants planned, started 2026-09-25. Conditions recorded: Melanoma. Interventions recorded: DNX-2401.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07444606","url":"https://clinicaltrials.gov/study/NCT07444606"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["melanoma"],"sections":[],"technologies":[],"targets":[],"drugs":["dnx-2401"],"companies":["dnatrix"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07444606","phase":"1","setting":"Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases","sponsor":"M.D. Anderson Cancer Center","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07444606/","neighbours":{"cancer":[{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"}],"drug":[{"id":"dnx-2401","kind":"drug","name":"DNX-2401","route":"/drugs/dnx-2401/"}],"company":[{"id":"dnatrix","kind":"company","name":"DNAtrix","route":"/companies/dnatrix/"}]}}