{"entity":{"id":"nct07448077","kind":"trial","name":"Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Hebei Medical University Fourth Hospital, now recruiting.","summary":"Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC is a phase 2, randomised interventional study registered as NCT07448077 by Hebei Medical University Fourth Hospital, with a registry enrolment figure of 128 participants, started 2026-03-01 and due to reach its primary completion in 2026-03-01. Interventions recorded: Experimental: short-course radiotherapy and immunotherapy; Chemoradiotherapy. Conditions listed: Efficacy and Safety of Short-course Radiotherapy in Total Neoadjuvant Therapy Combined With Enlonstobart for pMMR Locally Advanced Rectal Cancer. Primary outcome: complete response Rate (pCR+cCR ). Colorectal eligibility wording from the registry: \"Histologically confirmed adenocarcinoma of the colon, and umor biopsy immunohistochemistry (IHC) indicates pMMR\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07448077","url":"https://clinicaltrials.gov/study/NCT07448077"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07448077","phase":"2","setting":"Short-Course Radiotherapy in Total Neoadjuvant Therapy Combined With Enlonstobart for pMMR Locally Advanced Rectal Cancer: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial","sponsor":"Hebei Medical University Fourth Hospital","enrolled":128,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07448077/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}