{"entity":{"id":"nct07455734","kind":"trial","name":"Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of BNT3214 in advanced solid tumours, run by BioNTech SE, now recruiting.","summary":"Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07455734 by BioNTech SE, with 533 participants planned, started 2026-03-30 and due to reach its primary completion in 2030-10. Interventions recorded: BNT3214.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07455734","url":"https://clinicaltrials.gov/study/NCT07455734"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["biontech"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07455734","phase":"1/2","setting":"A Phase I/IIa, First-in-human, Open-label, Multi-site, Multi-regional, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors","sponsor":"BioNTech SE","enrolled":533,"outcomes":[]},"route":"/trials/nct07455734/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"company":[{"id":"biontech","kind":"company","name":"BioNTech","route":"/companies/biontech/"}]}}