{"entity":{"id":"nct07455903","kind":"trial","name":"Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT","aka":[],"tldr":"A phase 2 trial of Leuprolide, Degarelix, Relugolix, Triptorelin, Bicalutamide and Flotufolastat F-18 in Prostate cancer, run by Baptist Health South Florida, now recruiting.","summary":"Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT is a phase 2 interventional study registered as NCT07455903 by Baptist Health South Florida, with 50 participants planned, started 2026-07-29 and due to reach its primary completion in 2030-02. Interventions recorded: Leuprolide, Degarelix, Relugolix, Triptorelin, Bicalutamide, 18-F Flotufolastat PSMA PET, Radical prostatectomy. Conditions recorded: Prostate Cancer, Localized Prostate Carcinoma.\n\nLinked to the drug Flotufolastat F-18 because the registry names it among its interventions and Prostate cancer among its conditions. Registry record only: no result has been read by an editor.","status":"recruiting","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT07455903","url":"https://clinicaltrials.gov/study/NCT07455903"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["prostate"],"sections":[],"technologies":[],"targets":[],"drugs":["leuprolide","degarelix","relugolix","triptorelin","bicalutamide","flotufolastat"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07455903","phase":"2","setting":"Assessing the Efficacy of Neoadjuvant Androgen Deprivation Therapy (ADT) Utilizing 18F-Flotufolastat PSMA PET/CT in Patients With High-Risk Localized Prostate Cancer (LHRPC)","sponsor":"Baptist Health South Florida","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07455903/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"drug":[{"id":"bicalutamide","kind":"drug","name":"Bicalutamide","route":"/drugs/bicalutamide/"},{"id":"degarelix","kind":"drug","name":"Degarelix","route":"/drugs/degarelix/"},{"id":"flotufolastat","kind":"drug","name":"Flotufolastat F-18","route":"/drugs/flotufolastat/"},{"id":"leuprolide","kind":"drug","name":"Leuprolide (leuprorelin) and GnRH agonists","route":"/drugs/leuprolide/"},{"id":"relugolix","kind":"drug","name":"Relugolix","route":"/drugs/relugolix/"},{"id":"triptorelin","kind":"drug","name":"Triptorelin","route":"/drugs/triptorelin/"}]}}