{"entity":{"id":"nct07477808","kind":"trial","name":"Megestrol Acetate for First-Line Treatment of Malnourished Non-Small Cell Lung Cancer","aka":[],"tldr":"A phase 3 trial in lung cancer, run by Hunan Province Tumor Hospital, not yet recruiting.","summary":"Megestrol Acetate for First-Line Treatment of Malnourished Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT07477808 by Hunan Province Tumor Hospital, with a registry enrolment figure of 116 participants, started 2026-04-01 and due to reach its primary completion in 2028-04-01. Interventions recorded: Nanocrystalline Megestrol Acetate Oral Suspension; PD-1/L1 inhibitor combined with chemotherapy. Conditions listed: Non-small Cell Lung Cancer. Primary outcome: change in body weight. Lung eligibility wording from the registry: \"* According to the 8th edition of the Lung Cancer TNM Staging Classification by the International Association for the Study of Lung Cancer (IASLC) and the American Joint Committee on Cancer (AJCC), subjects have histologically or cytologically confirmed locally advanced (Stage IIIB/IIIC) or metastat\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07477808","url":"https://clinicaltrials.gov/study/NCT07477808"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07477808","phase":"3","setting":"A Prospective, Randomized, Parallel-Controlled Clinical Study of Megestrol Acetate Oral Suspension for First-Line Treatment of Malnourished Non-Small Cell Lung Cancer","sponsor":"Hunan Province Tumor Hospital","enrolled":116,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07477808/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}