{"entity":{"id":"nct07478731","kind":"trial","name":"Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer","aka":["MA-CRC-II-018"],"tldr":"A phase 2 trial in colorectal cancer, run by Hong Qiu, now recruiting.","summary":"Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer is a phase 2, interventional study registered as NCT07478731 by Hong Qiu, with a registry enrolment figure of 48 participants, started 2025-12-20 and due to reach its primary completion in 2027-12-31. Interventions recorded: SHR-1701 neoadjuvant. Conditions listed: CRC (Colorectal Cancer). Primary outcome: pCR. Colorectal eligibility wording from the registry: \"3: Pathologically confirmed rectal adenocarcinoma（At least meet any of the following criteria：cT3-4、cN2、EMVI+、MRF+）\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07478731","url":"https://clinicaltrials.gov/study/NCT07478731"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07478731","phase":"2","setting":"A Phase II, Prospective, Single Arm Study of Neoadjuvant SHR-1701 Combine With Chemoradiotherapy for Locally Advanced Rectal Cancer","sponsor":"Hong Qiu","enrolled":48,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07478731/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}