{"entity":{"id":"nct07504198","kind":"trial","name":"Neuroprotection of Memantine and Rosuvastatin","aka":[],"tldr":"A phase 2/3 trial of memantine in colorectal cancer, run by Tanta University, not yet recruiting.","summary":"Neuroprotection of Memantine and Rosuvastatin is a phase 2/3, randomised interventional study registered as NCT07504198 by Tanta University, with a registry enrolment figure of 46 participants, started 2026-03 and due to reach its primary completion in 2027-04. Interventions recorded: Starch Placebo; Memantine; Rosuvastatin 20 Mg Oral Tablet. Conditions listed: Peripheral Nerve Disease. Primary outcome: The primary outcome is the percentage of patients with sensory neuropathy grade ≥ 2 according to National Cancer Institute Common Terminology Criteria for Adverse Events for grading of neuropathy from 1 to 5 based on severity.. Colorectal eligibility wording from the registry: \"* Patients with histologically confirmed diagnosis of stage III or stage IV colorectal cancer\". Sites: Egypt. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07504198","url":"https://clinicaltrials.gov/study/NCT07504198"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["memantine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07504198","phase":"2/3","setting":"Neuroprotective Effect of Memantine and Rosuvastatin Against Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer","sponsor":"Tanta University","enrolled":46,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07504198/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"drug":[{"id":"memantine","kind":"drug","name":"Memantine","route":"/drugs/memantine/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}