{"entity":{"id":"nct07504471","kind":"trial","name":"Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metast","aka":[],"tldr":"A phase 2 trial in pancreatic cancer, run by Ruijin Hospital, now recruiting.","summary":"Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metastases is a phase 2, interventional study registered as NCT07504471 by Ruijin Hospital, with a registry enrolment figure of 50 participants, started 2026-03-23 and due to reach its primary completion in 2026-12-31. Interventions recorded: pH-NASOX-Immune Group. Conditions listed: Pancreatic Neoplasms; Hepatic Metastasis of Pancreatic Cancer. Primary outcome: Overall Survival (OS). Pancreatic eligibility wording from the registry: \"* Pathologically confirmed pancreatic cancer (originating from the pancreatic ductal epithelium), with metastasis to the liver;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07504471","url":"https://clinicaltrials.gov/study/NCT07504471"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07504471","phase":"2","setting":"A Prospective, Single-Center, Phase II Clinical Study of Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen (Liposomal Irinotecan, Oxaliplatin, and S-1) Hepatic Arterial Infusion Chemotherapy (HAIC) and Intra-Arterial Programmed Death-1 (PD-1) Inhibitors for Liver Metastases From Pancreatic Cancer","sponsor":"Ruijin Hospital","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07504471/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}