{"entity":{"id":"nct07509398","kind":"trial","name":"FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer","aka":[],"tldr":"A phase 2/3 trial in colorectal cancer, run by Shanghai 10th People's Hospital, not yet recruiting.","summary":"FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer is a phase 2/3, randomised interventional study registered as NCT07509398 by Shanghai 10th People's Hospital, with a registry enrolment figure of 220 participants, started 2026-04 and due to reach its primary completion in 2027-12. Interventions recorded: Standard First-Line Therapy; FMT Combined with Standard First-Line Therapy. Conditions listed: Unresectable Colorectal Cancer; Colorectal Cancer (Locally Advanced or Metastatic). Primary outcome: Objective Response Rate. Colorectal eligibility wording from the registry: \"(3) Meet the defined criteria for initially unresectable advanced metastatic colorectal cancer (mCRC) for this project\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07509398","url":"https://clinicaltrials.gov/study/NCT07509398"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07509398","phase":"2/3","setting":"Efficacy and Safety of Fecal Microbiota Transplantation Combined With First-Line Standard Therapy in Patients With Initially Unresectable Colorectal Cancer: A Multicenter, Open-Label, Randomized Controlled Trial","sponsor":"Shanghai 10th People's Hospital","enrolled":220,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07509398/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}