{"entity":{"id":"nct07551479","kind":"trial","name":"SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer","aka":["TORCH-STAR"],"tldr":"A phase 3 trial of capecitabine and fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by Fudan University, not yet recruiting.","summary":"SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer is a phase 3, randomised interventional study registered as NCT07551479 by Fudan University, with a registry enrolment figure of 612 participants, started 2026-05-01 and due to reach its primary completion in 2032-12-31. Interventions recorded: short-course radiaotherapy; long-course chemoradiaothearpy; Capecitabine; Oxaliplatin; PD-1 inhibitor. Conditions listed: Locally Advanced Rectal Cancer (LARC); MSS (Microsatellite Stable). Primary outcome: 3 year event-free survival rate. Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07551479","url":"https://clinicaltrials.gov/study/NCT07551479"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy","imrt-igrt","platinum"],"targets":[],"drugs":["capecitabine","folfox"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07551479","phase":"3","setting":"SCRT Followed by CAPOX and PD-1 Inhibitor Versus LCCRT Followed by CAPOX in Total Neoadjuvant Treatment for High-risk LARC: A Prospective, Randomized, Multicenter, Phase III Study","sponsor":"Fudan University","enrolled":612,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07551479/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"},{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"capecitabine","kind":"drug","name":"Capecitabine","route":"/drugs/capecitabine/"},{"id":"folfox","kind":"drug","name":"FOLFOX (5-FU, leucovorin, oxaliplatin)","route":"/drugs/folfox/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}