{"entity":{"id":"nct07573111","kind":"trial","name":"Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation","aka":[],"tldr":"A phase 1 trial of QUAIL-100 run by Laguna Biotherapeutics, Inc., now recruiting.","summary":"Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation is a phase 1 interventional study registered as NCT07573111 by Laguna Biotherapeutics, Inc., with 12 participants planned, started 2026-08. Conditions recorded: Acute Leukemia and Myelodysplastic Syndrome. Interventions recorded: QUAIL-100.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07573111","url":"https://clinicaltrials.gov/study/NCT07573111"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["all-leukemia","mds"],"sections":[],"technologies":[],"targets":[],"drugs":["quail-100"],"companies":["laguna-biotherapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07573111","phase":"1","setting":"An Open-label, First-in-Human, Single Ascending Dose Study of QUAIL-100 in Pediatric and Young Adult Subjects With High-Risk Acute Leukemias and Myelodysplastic Syndrome Who Have Received a T-cell Receptor (TCR) αβ+ T Cell/CD-19+ B Cell-Depleted Hematopoietic Stem Cell Transplantation","sponsor":"Laguna Biotherapeutics, Inc.","enrolled":12,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07573111/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"mds","kind":"cancer","name":"Myelodysplastic syndromes / neoplasms (MDS)","route":"/cancers/mds/"}],"drug":[{"id":"quail-100","kind":"drug","name":"QUAIL-100","route":"/drugs/quail-100/"}],"company":[{"id":"laguna-biotherapeutics","kind":"company","name":"Laguna Biotherapeutics","route":"/companies/laguna-biotherapeutics/"}]}}