{"entity":{"id":"nct07619898","kind":"trial","name":"PHOENIX-ECP- Extracorporeal Photopheresis for Immune-related Colitis and/or Hepatitis in Advanced Melanoma With Inadequate Response to Steroid Exposure","aka":[],"tldr":"A phase 2 trial of Methoxsalen in Skin cancer and Melanoma, run by Therakos LLC, not yet recruiting.","summary":"PHOENIX-ECP- Extracorporeal Photopheresis for Immune-related Colitis and/or Hepatitis in Advanced Melanoma With Inadequate Response to Steroid Exposure is a phase 2 interventional study registered as NCT07619898 by Therakos LLC, with 112 participants planned, started 2026-07 and due to reach its primary completion in 2028-12. Interventions recorded: methoxsalen, Extracorporeal photopheresis (ECP), Vedolizumab, Infliximab, Mycophenolate Mofetil (MMF), Azathioprine. Conditions recorded: Colitis, Hepatitis, Melanoma (Skin Cancer).\n\nLinked to the drug Methoxsalen because the registry names it among its interventions and Skin cancer and Melanoma among its conditions. Registry record only: no result has been read by an editor.","status":"planned","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT07619898","url":"https://clinicaltrials.gov/study/NCT07619898"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["skin-cancer","melanoma"],"sections":[],"technologies":[],"targets":[],"drugs":["methoxsalen-ecp"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07619898","phase":"2","setting":"PHOENIX- A Phase 2, Randomized, Controlled, Open-label, Multicenter Study to Evaluate the Efficacy and Safety/Tolerability of Extracorporeal Photopheresis (ECP) Versus Best Available Therapy (BAT) for the Treatment of Immune-related Colitis or Hepatitis With Inadequate Response to Corticosteroids in Participants With Unresectable or Metastatic Melanoma Treated With Immune Checkpoint Inhibitors (ICI)","sponsor":"Therakos LLC","enrolled":112,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07619898/","neighbours":{"cancer":[{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"},{"id":"skin-cancer","kind":"cancer","name":"Skin cancer (all types)","route":"/cancers/skin-cancer/"}],"drug":[{"id":"methoxsalen-ecp","kind":"drug","name":"Methoxsalen (extracorporeal photopheresis)","route":"/drugs/methoxsalen-ecp/"}]}}