{"entity":{"id":"nct07620548","kind":"trial","name":"Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas","aka":[],"tldr":"A phase 2 trial of Laser interstitial thermal therapy systems in Glioma & glioblastoma, run by Washington University School of Medicine, not yet recruiting.","summary":"Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas is a phase 2 interventional study registered as NCT07620548 by Washington University School of Medicine, with 99 participants planned, started 2026-08-31 and due to reach its primary completion in 2031-02-28. Interventions recorded: NeuroBlate® Laser Ablation Laser Interstitial Thermal Therapy, Cemiplimab, Chemotherapy. Conditions recorded: Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype.\n\nLinked to the technology Laser interstitial thermal therapy systems because the registry names it (\"neuroblate\") among its interventions and Glioma & glioblastoma among its conditions. Registry record only: no result has been read by an editor.","status":"planned","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT07620548","url":"https://clinicaltrials.gov/study/NCT07620548"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["glioblastoma"],"sections":[],"technologies":["litt-systems"],"targets":[],"drugs":["cemiplimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07620548","phase":"2","setting":"A Randomized Phase II Study of the Efficacy of Laser Interstitial Thermal Therapy (LiTT) Combined With Cemiplimab Versus Physician's Choice Chemotherapy in Recurrent Glioblastomas","sponsor":"Washington University School of Medicine","enrolled":99,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07620548/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"technology":[{"id":"litt-systems","kind":"technology","name":"Laser interstitial thermal therapy systems (NeuroBlate, Visualase)","route":"/technologies/litt-systems/"}],"drug":[{"id":"cemiplimab","kind":"drug","name":"Cemiplimab","route":"/drugs/cemiplimab/"}]}}