{"entity":{"id":"nct07622550","kind":"trial","name":"A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated A","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Jiangsu Cancer Institute & Hospital, not yet recruiting.","summary":"A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance is a phase 2, interventional study registered as NCT07622550 by Jiangsu Cancer Institute & Hospital, with a registry enrolment figure of 80 participants, started 2026-06-15 and due to reach its primary completion in 2027-12-15. Interventions recorded: Serplulimab+Fruquintinib+XELOX. Conditions listed: Metastatic Colorectal Cancer (CRC). Primary outcome: Investigator-assessed Progression-Free Survival（PFS）. Colorectal eligibility wording from the registry: \"* Diagnosis of advanced unresectable or metastatic colorectal cancer\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07622550","url":"https://clinicaltrials.gov/study/NCT07622550"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07622550","phase":"2","setting":"A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance","sponsor":"Jiangsu Cancer Institute & Hospital","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07622550/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}