{"entity":{"id":"nct07650357","kind":"trial","name":"A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)","aka":[],"tldr":"A phase 1 trial of CLSP-5282 run by Clasp Therapeutics, Inc., not yet recruiting.","summary":"A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101) is a phase 1 interventional study registered as NCT07650357 by Clasp Therapeutics, Inc., with 140 participants planned, started 2026-07. Conditions recorded: Advanced Solid Tumor, Non Small Cell Lung Cancer, Pancreatic Carcinoma and Colorectal Cancer. Interventions recorded: CLSP-5282.","status":"planned","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07650357","url":"https://clinicaltrials.gov/study/NCT07650357"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","nsclc","pancreatic","colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":["clsp-5282"],"companies":["clasp-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07650357","phase":"1","setting":"SENTINEL-101: A Phase 1 Dose Escalation and Expansion Study of CLSP-5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors That Harbor the KRas G12V Mutation","sponsor":"Clasp Therapeutics, Inc.","enrolled":140,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07650357/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"drug":[{"id":"clsp-5282","kind":"drug","name":"CLSP-5282","route":"/drugs/clsp-5282/"}],"company":[{"id":"clasp-therapeutics","kind":"company","name":"Clasp Therapeutics","route":"/companies/clasp-therapeutics/"}]}}