{"entity":{"id":"nct07667296","kind":"trial","name":"APG-157 in Locally Advanced Head and Neck Squamous Cell Carcinoma","aka":[],"tldr":"A phase 3 trial of APG-157 run by Aveta Biomics, Inc., not yet recruiting.","summary":"APG-157 in Locally Advanced Head and Neck Squamous Cell Carcinoma is a phase 3 interventional study registered as NCT07667296 by Aveta Biomics, Inc., with 826 participants planned, started 2026-07. Conditions recorded: Head and Neck Cancer, Head and Neck (HNSCC), Oropharyngeal, Oral Cavity, Oral Cavity Carcinoma, Oropharynx Squamous Cell Carcinoma and Oral Cavity Squamous Cell Carcinoma. Interventions recorded: APG-157, Surgery, Radiation/Chemotherapy and Radiation/Chemotherapy.","status":"planned","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07667296","url":"https://clinicaltrials.gov/study/NCT07667296"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck","oropharyngeal-cancer","oral-cavity-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["apg-157"],"companies":["aveta-biomics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07667296","phase":"3","setting":"A Multicenter, Randomized, Open-Label Phase 3 Study of APG-157 as Neoadjuvant Therapy or as Induction and Maintenance Therapy in Locally Advanced Head and Neck Squamous Cell Carcinoma","sponsor":"Aveta Biomics, Inc.","enrolled":826,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07667296/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"oral-cavity-cancer","kind":"cancer","name":"Oral cavity cancer (mouth and tongue)","route":"/cancers/oral-cavity-cancer/"},{"id":"oropharyngeal-cancer","kind":"cancer","name":"Oropharyngeal cancer (tonsil and base of tongue)","route":"/cancers/oropharyngeal-cancer/"}],"drug":[{"id":"apg-157","kind":"drug","name":"APG-157","route":"/drugs/apg-157/"}],"company":[{"id":"aveta-biomics","kind":"company","name":"Aveta Biomics","route":"/companies/aveta-biomics/"}]}}