{"entity":{"id":"nct07670312","kind":"trial","name":"Evaluation of XYA02 in Patients With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial in pancreatic cancer, run by XYone Therapeutics, Inc, not yet recruiting.","summary":"Evaluation of XYA02 in Patients With Advanced Solid Tumors is a phase 1/2, interventional study registered as NCT07670312 by XYone Therapeutics, Inc, with a registry enrolment figure of 190 participants, started 2026-07-15 and due to reach its primary completion in 2029-07-15. Interventions recorded: XYA02. Conditions listed: MUC1-expressing Advanced, Relapsed and/or Refractory Solid Tumors; Non-Small Cell Lung Cancer; Ovarian Cancer; GEJ Adenocarcinoma; Colorectal Cancer; Pancreatic Adenocarcinoma. Primary outcome: Frequency of Treatment Emergent Adverse Events of XYA02; Duration of Treatment Emergent Adverse Events of XYA02; Severity of Treatment Emergent Adverse Events of XYA02. Pancreatic eligibility wording from the registry: \"Cohort 2E: Pancreatic cancer\". Sites: Australia. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07670312","url":"https://clinicaltrials.gov/study/NCT07670312"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07670312","phase":"1/2","setting":"A Phase 1b/2, Multicenter, Non-randomized, Open-label, Multiple Dose First- In-Human Study of XYA02 in Patients With Advanced Solid Tumors","sponsor":"XYone Therapeutics, Inc","enrolled":190,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07670312/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}