{"entity":{"id":"nct07683403","kind":"trial","name":"Savolitinib Plus Cetuximab and FOLFOX Chemotherapy for RAS/BRAF Wild-type Metastatic Colorectal Cancer","aka":[],"tldr":"A phase 1/2 trial in colorectal cancer, run by Fudan University, not yet recruiting.","summary":"Savolitinib Plus Cetuximab and FOLFOX Chemotherapy for RAS/BRAF Wild-type Metastatic Colorectal Cancer is a phase 1/2, randomised interventional study registered as NCT07683403 by Fudan University, with a registry enrolment figure of 138 participants, started 2026-06-30 and due to reach its primary completion in 2028-06-30. Interventions recorded: Savolitinib plus cetuximab and FOLFOX chemotherapy; Cetuximab and FOLFOX chemotherapy. Conditions listed: Colorectal Cancer (CRC). Primary outcome: Objective response rate (ORR). Colorectal eligibility wording from the registry: \"Histologically confirmed unresectable locally advanced or metastatic colorectal cancer;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07683403","url":"https://clinicaltrials.gov/study/NCT07683403"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07683403","phase":"1/2","setting":"Savolitinib Plus Cetuximab and FOLFOX Chemotherapy Versus Cetuximab and FOLFOX Chemotherapy as First-line Treatment for RAS/BRAF Wild-type Metastatic Colorectal Cancer: a Prospective, Randomized, Controlled, Multicenter, Open-label Study","sponsor":"Fudan University","enrolled":138,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07683403/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}