{"entity":{"id":"nct07688577","kind":"trial","name":"XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial in lung cancer, run by Xilio Development, Inc., not yet recruiting.","summary":"XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors is a phase 1/2, interventional study registered as NCT07688577 by Xilio Development, Inc., with a registry enrolment figure of 140 participants, started 2026-08 and due to reach its primary completion in 2029-11. Interventions recorded: XTX501. Conditions listed: Metastatic NSCLC - Non-Small Cell Lung Cancer; Advanced Solid Tumor. Primary outcome: Incidence of Dose Limiting Toxicities (DLTs) in Part 1A; Incidence of treatment-emergent adverse events (Phase 1 and Phase 2); Incidence of serious adverse events (Phase 1 and Phase 2). Lung eligibility wording from the registry: \"* Metastatic NSCLC:\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07688577","url":"https://clinicaltrials.gov/study/NCT07688577"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["xilio-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07688577","phase":"1/2","setting":"A First-in-Human, Multicenter, Phase 1/2, Open-Label Study of XTX501 in Participants With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors","sponsor":"Xilio Development, Inc.","enrolled":140,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07688577/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"company":[{"id":"xilio-therapeutics","kind":"company","name":"Xilio Therapeutics","route":"/companies/xilio-therapeutics/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}