{"entity":{"id":"nct07689539","kind":"trial","name":"Trial of DN022150 Versus Chemotherapy in Previously Treated Advanced Pancreatic Cancer With KRAS G12D Mutation","aka":[],"tldr":"A phase 3 trial in pancreatic cancer, run by Jiangxi Kvvit Pharmaceutical Co., Ltd., not yet recruiting.","summary":"Trial of DN022150 Versus Chemotherapy in Previously Treated Advanced Pancreatic Cancer With KRAS G12D Mutation is a phase 3, randomised interventional study registered as NCT07689539 by Jiangxi Kvvit Pharmaceutical Co., Ltd., with a registry enrolment figure of 360 participants, started 2026-09 and due to reach its primary completion in 2028-07. Interventions recorded: DN022150; Chemotherapy. Conditions listed: Pancreatic Cancer. Primary outcome: Progression-Free Survival (PFS); Overall Survival (OS). Pancreatic eligibility wording from the registry: \"Subjects with confirmed KRAS G12D who have received prior systemic therapy for advanced or metastatic pancreatic cancer\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07689539","url":"https://clinicaltrials.gov/study/NCT07689539"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07689539","phase":"3","setting":"A Phase 3, Multicenter, Open-Label, Randomized, Controlled Trial of DN022150 Monotherapy Versus Investigator's Choice Chemotherapy in Previously Treated Advanced Pancreatic Cancer With KRAS G12D Mutation","sponsor":"Jiangxi Kvvit Pharmaceutical Co., Ltd.","enrolled":360,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07689539/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}