{"entity":{"id":"nct07689955","kind":"trial","name":"A Phase-II Clinical Trial of Radiotherapy to the Coeliac Plexus to Help Pain in Advanced Pancreatic Cancer","aka":["PANCPLEX"],"tldr":"A phase 2 trial in pancreatic cancer, run by Royal Marsden NHS Foundation Trust, not yet recruiting.","summary":"A Phase-II Clinical Trial of Radiotherapy to the Coeliac Plexus to Help Pain in Advanced Pancreatic Cancer is a phase 2, interventional study registered as NCT07689955 by Royal Marsden NHS Foundation Trust, with a registry enrolment figure of 52 participants, started 2026-09 and due to reach its primary completion in 2029-09. Interventions recorded: IMRT. Conditions listed: Pancreatic Cancer. Primary outcome: To assess the clinical benefit of IMRT radiotherapy to the coeliac plexus in achieving a clinically meaningful reduction in participant-reported pain in participants with inoperable advanced pancreatic adenocarcinoma.. Pancreatic eligibility wording from the registry: \"Pain with a BPI score ≥ 2 as a result of pancreatic adenocarcinoma, not sufficiently responding to opiate medication\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07689955","url":"https://clinicaltrials.gov/study/NCT07689955"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07689955","phase":"2","setting":"A Multi-Centre, Single-Arm Prospective Phase II Clinical Trial of Radiotherapy to the Coeliac Plexus to Help Pain in Advanced Pancreatic Cancer","sponsor":"Royal Marsden NHS Foundation Trust","enrolled":52,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07689955/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}