{"entity":{"id":"nct07705035","kind":"trial","name":"DBC-664 in Adult Patients With Solid Tumors","aka":[],"tldr":"A phase 1 trial of DBC-664 run by Duboce Biopharmaceuticals, Inc., now recruiting.","summary":"DBC-664 in Adult Patients With Solid Tumors is a phase 1 interventional study registered as NCT07705035 by Duboce Biopharmaceuticals, Inc., with 210 participants planned, started 2026-07-17. Conditions recorded: Malignant Germ Cell Tumor, Lung Adenocarcinoma, Gastric/Esophageal/Gastroesophageal Junction (GEJ) Adenocarcinoma, Urothelial Carcinoma, Endometrial Adenocarcinoma and Ovarian Adenocarcinoma. Interventions recorded: DBC-664.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07705035","url":"https://clinicaltrials.gov/study/NCT07705035"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["lung-adenocarcinoma","gastric","urothelial","endometrial","ovarian"],"sections":[],"technologies":[],"targets":[],"drugs":["dbc-664"],"companies":["duboce-biopharmaceuticals"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07705035","phase":"1","setting":"A Phase 1a/1b Open Label, Multicenter, Dose Escalation and Dose Expansion Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Activity of DBC-664 in Adult Patients With Locally Advanced or Metastatic Solid Tumors","sponsor":"Duboce Biopharmaceuticals, Inc.","enrolled":210,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07705035/","neighbours":{"cancer":[{"id":"lung-adenocarcinoma","kind":"cancer","name":"Adenocarcinoma of the lung","route":"/cancers/lung-adenocarcinoma/"},{"id":"urothelial","kind":"cancer","name":"Bladder & urothelial cancer","route":"/cancers/urothelial/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"}],"drug":[{"id":"dbc-664","kind":"drug","name":"DBC-664","route":"/drugs/dbc-664/"}],"company":[{"id":"duboce-biopharmaceuticals","kind":"company","name":"Duboce Biopharmaceuticals","route":"/companies/duboce-biopharmaceuticals/"}]}}