{"entity":{"id":"nct07729605","kind":"trial","name":"FOLFIRI Plus Bevacizuamb and QL1706 in Second-Line Treatment for mCRC","aka":["FIRBIT"],"tldr":"A phase 3 trial in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.","summary":"FOLFIRI Plus Bevacizuamb and QL1706 in Second-Line Treatment for mCRC is a phase 3, randomised interventional study registered as NCT07729605 by Sun Yat-sen University, with a registry enrolment figure of 270 participants, started 2026-07-30 and due to reach its primary completion in 2028-12-30. Interventions recorded: FOLFIRI + bevacizumab + QL1706; FOLFIRI + bevacizumab. Conditions listed: Colorectal Cancer Metastatic; Microsatellite Stable (MSS) Colorectal Cancer (CRC). Primary outcome: Progression-free survival (PFS). Colorectal eligibility wording from the registry: \"Histologically confirmed metastatic colorectal adenocarcinoma with pMMR/MSS status\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07729605","url":"https://clinicaltrials.gov/study/NCT07729605"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07729605","phase":"3","setting":"FOLFIRI Plus Bevacizuamb With or Without Iparomlimab and Tuvonralimab as Second-Line Treatment for Metastatic Colorectal Cancer: A Randomized Controlled Trial","sponsor":"Sun Yat-sen University","enrolled":270,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07729605/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}