{"entity":{"id":"nct07730021","kind":"trial","name":"A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of Pembrolizumab, Carboplatin and Oxaliplatin in advanced solid tumours, run by Astellas Pharma Global Development, Inc., now recruiting.","summary":"A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors is a phase 1/2 interventional study registered as NCT07730021 by Astellas Pharma Global Development, Inc., with 392 participants planned, started 2026-09-02 and due to reach its primary completion in 2030-02-28. Interventions recorded: ASP388B, Pembrolizumab, Carboplatin, Oxaliplatin and 5-fluorouracil.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07730021","url":"https://clinicaltrials.gov/study/NCT07730021"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["pembrolizumab","carboplatin","oxaliplatin"],"companies":["astellas"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07730021","phase":"1/2","setting":"A Phase 1b/2 Study of ASP388B as Monotherapy and in Combination With Standard Therapies in Participants With Locally Advanced Unresectable or Metastatic Solid Tumors","sponsor":"Astellas Pharma Global Development, Inc.","enrolled":392,"outcomes":[]},"route":"/trials/nct07730021/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"carboplatin","kind":"drug","name":"Carboplatin","route":"/drugs/carboplatin/"},{"id":"oxaliplatin","kind":"drug","name":"Oxaliplatin","route":"/drugs/oxaliplatin/"},{"id":"pembrolizumab","kind":"drug","name":"Pembrolizumab","route":"/drugs/pembrolizumab/"}],"company":[{"id":"astellas","kind":"company","name":"Astellas","route":"/companies/astellas/"}]}}