{"entity":{"id":"nct07755124","kind":"trial","name":"Dietary Arginine Deprivation Combined With Chemoradiotherapy for Neoadjuvant Treatment of Rectal Cancer: A Randomized Controlled Trial","aka":[],"tldr":"A phase 1/2 trial in colorectal cancer, run by West China Hospital, not yet recruiting.","summary":"Dietary Arginine Deprivation Combined With Chemoradiotherapy for Neoadjuvant Treatment of Rectal Cancer: A Randomized Controlled Trial is a phase 1/2, randomised interventional study registered as NCT07755124 by West China Hospital, with a registry enrolment figure of 140 participants, started 2026-08-14 and due to reach its primary completion in 2028-08. Interventions recorded: Arginine-Deprived Diet; Short-Course Radiotherapy (SCRT); CAPOX + PD-1 Inhibitor. Conditions listed: Rectal Neoplasms. Primary outcome: Complete Response (CR) Rate (pCR + cCR). Colorectal eligibility wording from the registry: \"* Locally advanced mid-low rectal cancer staged as cT3, cT4, or node-positive by rectal MRI\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07755124","url":"https://clinicaltrials.gov/study/NCT07755124"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07755124","phase":"1/2","setting":"A Randomized Controlled Trial of Dietary Arginine Deprivation Combined With Chemoradiotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer","sponsor":"West China Hospital","enrolled":140,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07755124/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}