{"entity":{"id":"nct07765667","kind":"trial","name":"NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC","aka":[],"tldr":"A phase 2 trial of High-dose intravenous vitamin C in Rectal cancer, run by Sixth Affiliated Hospital, Sun Yat-sen University, not yet recruiting.","summary":"NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC is a phase 2 interventional study registered as NCT07765667 by Sixth Affiliated Hospital, Sun Yat-sen University, with 100 participants planned, started 2026-09-01 and due to reach its primary completion in 2029-09-01. Interventions recorded: Short-Course Radiotherapy, PD-1 monoclonal antibody, mFOLFOX6 regimen, Ketogenic Diet, Surgical resection, Vitamin C. Conditions recorded: Rectal Adenocarcinoma, High-Risk Cancer, MSS.\n\nLinked to the technology High-dose intravenous vitamin C because the registry's title names it (\"high dose intravenous vitamin c\") and Rectal cancer among its conditions. Registry record only: no result has been read by an editor.","status":"planned","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT07765667","url":"https://clinicaltrials.gov/study/NCT07765667"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["high-dose-vitamin-c"],"targets":[],"drugs":["folfox"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07765667","phase":"2","setting":"Neoadjuvant Chemoradiotherapy and Immunotherapy Combined With Ketogenic Diet and/or High-Dose Intravenous Vitamin C in pMMR/MSS Locally Advanced Rectal Adenocarcinoma: A Prospective, Multicenter, Phase Ⅱ Clinical Study (CRI-KEV Trial)","sponsor":"Sixth Affiliated Hospital, Sun Yat-sen University","enrolled":100,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07765667/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"high-dose-vitamin-c","kind":"technology","name":"High-dose intravenous vitamin C","route":"/technologies/high-dose-vitamin-c/"}],"drug":[{"id":"folfox","kind":"drug","name":"FOLFOX (5-FU, leucovorin, oxaliplatin)","route":"/drugs/folfox/"}]}}