{"entity":{"id":"nct07768436","kind":"trial","name":"A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer","aka":[],"tldr":"A phase 2 trial of paclitaxel / nab-paclitaxel in triple-negative breast cancer, run by Memorial Sloan Kettering Cancer Center, now recruiting.","summary":"A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer is a phase 2, interventional study registered as NCT07768436 by Memorial Sloan Kettering Cancer Center, with a registry enrolment figure of 76 participants, started 2026-08-11 and due to reach its primary completion in 2030-08-11. Interventions recorded: CMF Regimen; Paclitaxel. Conditions listed: Adenocarcinoma of the Breast; Breast Cancer; Triple Negative Breast Cancer. Triple-negative eligibility wording from the registry: \"* Cohort 2 only: Patients have triple negative (ER- (10%) PR-Her 2 Neu -) in the neoadjuvant setting\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07768436","url":"https://clinicaltrials.gov/study/NCT07768436"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["paclitaxel"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07768436","phase":"2","setting":"STUDY OF DOSE DENSE CMF (Cyclophosphamide, Methotrexate, Fluorouracil) as an Alternative to AC (Doxorubicin, Cyclophosphamide) in 2 Regimens in EARLY STAGE BREAST CANCER for Patients Greater or Equal to 70","sponsor":"Memorial Sloan Kettering Cancer Center","enrolled":76,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07768436/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}