{"entity":{"id":"nct07773363","kind":"trial","name":"Retlirafusp Alfa Plus Apatinib and Chemotherapy as Second-Line Treatment for Pancreatic Cancer","aka":[],"tldr":"A phase 2 trial of retlirafusp alfa and rivoceranib (apatinib) in pancreatic cancer, run by Tang-Du Hospital, not yet recruiting.","summary":"Retlirafusp Alfa Plus Apatinib and Chemotherapy as Second-Line Treatment for Pancreatic Cancer is a phase 2, interventional study registered as NCT07773363 by Tang-Du Hospital, with a registry enrolment figure of 37 participants, started 2026-08-30 and due to reach its primary completion in 2027-12-30. Interventions recorded: Retlirafusp Alfa; Apatinib; Fluoropyrimidine-Based Chemotherapy. Conditions listed: Pancreatic Cancer. Primary outcome: Progression-free survival. Pancreatic eligibility wording from the registry: \"Histologically or cytologically confirmed unresectable locally advanced or metastatic pancreatic cancer\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07773363","url":"https://clinicaltrials.gov/study/NCT07773363"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":["retlirafusp-alfa","rivoceranib"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07773363","phase":"2","setting":"A Prospective, Open-Label, Single-Arm Clinical Study of Retlirafusp Alfa Combined With Apatinib and Chemotherapy as Second-Line Treatment for Locally Advanced or Metastatic Pancreatic Cancer","sponsor":"Tang-Du Hospital","enrolled":37,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07773363/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"},{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"drug":[{"id":"retlirafusp-alfa","kind":"drug","name":"Retlirafusp alfa","route":"/drugs/retlirafusp-alfa/"},{"id":"rivoceranib","kind":"drug","name":"Rivoceranib (apatinib)","route":"/drugs/rivoceranib/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}