{"entity":{"id":"nct07779798","kind":"trial","name":"A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.","aka":[],"tldr":"A phase 1 trial of CBX-663 run by Crossbow Therapeutics, Inc., now recruiting.","summary":"A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma. is a phase 1 interventional study registered as NCT07779798 by Crossbow Therapeutics, Inc., with 120 participants planned, started 2026-08-04. Conditions recorded: Advanced Solid Tumors, Recurrent or Progressive Glioblastoma and Relapse or Refractory Myeloid Malignancies. Interventions recorded: CBX-663.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07779798","url":"https://clinicaltrials.gov/study/NCT07779798"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","glioblastoma","leukaemia"],"sections":[],"technologies":[],"targets":[],"drugs":["cbx-663"],"companies":["crossbow-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07779798","phase":"1","setting":"A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.","sponsor":"Crossbow Therapeutics, Inc.","enrolled":120,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07779798/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"},{"id":"leukaemia","kind":"cancer","name":"Leukaemia (all types)","route":"/cancers/leukaemia/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"cbx-663","kind":"drug","name":"CBX-663","route":"/drugs/cbx-663/"}],"company":[{"id":"crossbow-therapeutics","kind":"company","name":"Crossbow Therapeutics","route":"/companies/crossbow-therapeutics/"}]}}