{"entity":{"id":"nct07797244","kind":"trial","name":"A Single-Arm, Phase II Study of Retlirafusp Alfa in Combination With XELOX and Bevacizumab for the First-Line Treatment of Advanced RAS-Mutated Colorectal Cance","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Dai, Guanghai, not yet recruiting.","summary":"A Single-Arm, Phase II Study of Retlirafusp Alfa in Combination With XELOX and Bevacizumab for the First-Line Treatment of Advanced RAS-Mutated Colorectal Cancer With Liver Metastases (CRLM) is a phase 2, interventional study registered as NCT07797244 by Dai, Guanghai, with a registry enrolment figure of 46 participants, started 2026-10-29 and due to reach its primary completion in 2029-04. Interventions recorded: Retlirafusp alfa+XELOX+Bevacizumab Treatment. Conditions listed: Advanced RAS-Mutated Colorectal Cancer With Liver Metastases (CRLM). Primary outcome: Objective response rate (ORR). Colorectal eligibility wording from the registry: \"Unresectable colorectal adenocarcinoma confirmed by histopathology or cytology;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07797244","url":"https://clinicaltrials.gov/study/NCT07797244"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07797244","phase":"2","setting":"A Single-Arm, Phase II Study of Retlirafusp Alfa in Combination With XELOX and Bevacizumab for the First-Line Treatment of Advanced RAS-Mutated Colorectal Cancer With Liver Metastases (CRLM)","sponsor":"Dai, Guanghai","enrolled":46,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07797244/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}