{"entity":{"id":"nct07809256","kind":"trial","name":"A Prospective, Single-center, Non-randomized, Interventional Study on the Effectiveness and Safety of Combined Immunotargeted Therapy in Patients With Metastati","aka":["LPR-2"],"tldr":"A phase 3 trial in lung cancer, run by EuroCityClinic LLC, now recruiting.","summary":"A Prospective, Single-center, Non-randomized, Interventional Study on the Effectiveness and Safety of Combined Immunotargeted Therapy in Patients With Metastatic Non-small Cell Cancer With a RET Gene Translocation is a phase 3, interventional study registered as NCT07809256 by EuroCityClinic LLC, with a registry enrolment figure of 15 participants, started 2026-09 and due to reach its primary completion in 2028-08. Interventions recorded: lenvatinib pembrolizumab. Conditions listed: NSCLC (Non-small Cell Lung Cancer)R. Primary outcome: Progression-Free Survival (PFS); Objective Response Rate (ORR); Disease Control Rate (DCR). Lung eligibility wording from the registry: \"Have a confirmed diagnosis of metastatic non-small cell lung cancer (NSCLC), established by examination of a tumor tissue sample, with cancer that has spread to distant parts of the body\". Sites: Russia. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07809256","url":"https://clinicaltrials.gov/study/NCT07809256"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07809256","phase":"3","setting":"LPR-2: A Prospective, Single-center, Non-randomized, Interventional Study on the Effectiveness and Safety of Combined Immunotargeted Therapy in Patients With Metastatic Non-small Cell Cancer With a RET Gene Translocation","sponsor":"EuroCityClinic LLC","enrolled":15,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07809256/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}