{"entity":{"id":"nct07845266","kind":"trial","name":"Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GKL-006 Injection in Combination With TACE in Unresectable Hepatocellular Carcinoma","aka":[],"tldr":"A phase 1 trial of GKL-006 Injection run by Beijing Gene Key Life Technology Co., Ltd, completed.","summary":"Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GKL-006 Injection in Combination With TACE in Unresectable Hepatocellular Carcinoma is a phase 1 interventional study registered as NCT07845266 by Beijing Gene Key Life Technology Co., Ltd, with 13 participants enrolled, started 2024-04-16. Conditions recorded: Hepatocellular Carcinoma (HCC) and Unresectable Hepatocellular Carcinoma. Interventions recorded: GKL-006 Injection and transarterial chemoembolization.","status":"completed","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07845266","url":"https://clinicaltrials.gov/study/NCT07845266"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["hcc","hcc-advanced"],"sections":[],"technologies":[],"targets":[],"drugs":["gkl-006"],"companies":["beijing-gene-key-life-technology"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07845266","phase":"1","setting":"A Phase 1, Open-label, Controlled, Dose-escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of GKL-006 Injection in Combination With Transarterial Chemoembolization (TACE) Versus TACE Alone in Patients With Unresectable Hepatocellular Carcinoma","sponsor":"Beijing Gene Key Life Technology Co., Ltd","enrolled":13,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07845266/","neighbours":{"cancer":[{"id":"hcc-advanced","kind":"cancer","name":"Advanced hepatocellular carcinoma (BCLC C)","route":"/cancers/hcc-advanced/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"}],"drug":[{"id":"gkl-006","kind":"drug","name":"GKL-006 Injection","route":"/drugs/gkl-006/"}],"company":[{"id":"beijing-gene-key-life-technology","kind":"company","name":"Beijing Gene Key Life Technology","route":"/companies/beijing-gene-key-life-technology/"}]}}