{"entity":{"id":"nct07878988","kind":"trial","name":"This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors","aka":[],"tldr":"A phase 1 trial of LTZ-232 run by LTZ Therapeutics, Inc., now recruiting.","summary":"This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors is a phase 1 interventional study registered as NCT07878988 by LTZ Therapeutics, Inc., with 152 participants planned, started 2026-10-28. Conditions recorded: Colorectal Cancer, Advanced/Metastatic Solid Tumor, Solid Tumor (Phase I), EPCAM and Colon Cancer. Interventions recorded: LTZ-232.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07878988","url":"https://clinicaltrials.gov/study/NCT07878988"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["colorectal","metastatic-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["ltz-232"],"companies":["ltz-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07878988","phase":"1","setting":"A Phase 1/1b, Muticenter Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors","sponsor":"LTZ Therapeutics, Inc.","enrolled":152,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07878988/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"ltz-232","kind":"drug","name":"LTZ-232","route":"/drugs/ltz-232/"}],"company":[{"id":"ltz-therapeutics","kind":"company","name":"LTZ Therapeutics","route":"/companies/ltz-therapeutics/"}]}}