{"entity":{"id":"nct07909031","kind":"trial","name":"CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of CR-002 run by Crescent Biopharma, Inc., now recruiting.","summary":"CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT07909031 by Crescent Biopharma, Inc., with 219 participants planned, started 2026-10-21. Conditions recorded: Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Gastric/GEJ, Biliary Tract Cancer (BTC), Esophageal Squamous Cell Carcinoma (ESCC), Ovarian Cancer, Endometrial Cancer, Cervical Cancer Metastatic and Non-small Cell Lung Cancer (NSCLC). Interventions recorded: CR-002.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07909031","url":"https://clinicaltrials.gov/study/NCT07909031"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck","gastric","biliary-tract-cancer","oesophageal-squamous-cell-carcinoma","ovarian","endometrial","metastatic-cancer","nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["cr-002"],"companies":["crescent-biopharma"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07909031","phase":"1/2","setting":"A Phase 1/2, Multicenter, Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors","sponsor":"Crescent Biopharma, Inc.","enrolled":219,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07909031/","neighbours":{"cancer":[{"id":"biliary-tract-cancer","kind":"cancer","name":"Biliary tract cancer (all types)","route":"/cancers/biliary-tract-cancer/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"oesophageal-squamous-cell-carcinoma","kind":"cancer","name":"Oesophageal squamous cell carcinoma","route":"/cancers/oesophageal-squamous-cell-carcinoma/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"}],"drug":[{"id":"cr-002","kind":"drug","name":"CR-002","route":"/drugs/cr-002/"}],"company":[{"id":"crescent-biopharma","kind":"company","name":"Crescent Biopharma","route":"/companies/crescent-biopharma/"}]}}