{"entity":{"id":"paper-ata-2015-thyroid-nodules-dtc-haugen-thyroid-2016","kind":"paper","name":"2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer","aka":[],"tldr":"The 2015 American Thyroid Association guideline moved differentiated thyroid cancer towards less treatment: lobectomy rather than total thyroidectomy for many low-risk cancers, selective rather than routine radioactive iodine, and active surveillance for small papillary cancers.","summary":"Comprehensive guideline covering evaluation of thyroid nodules, ultrasound risk stratification, molecular testing, extent of surgery, risk stratification for recurrence, radioactive iodine indications, TSH suppression, follow-up, and management of recurrent and metastatic differentiated thyroid cancer including kinase inhibitors.","asOf":"2026-09-17","links":[{"label":"Thyroid 2016","url":"https://doi.org/10.1089/thy.2015.0020"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/26462967/"}],"tags":[],"related":[],"cancers":["follicular-thyroid-cancer","papillary-thyroid-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"journal":"Thyroid","year":2016,"doi":"10.1089/thy.2015.0020","pmid":"26462967","authors":"Haugen BR, Alexander EK, Bible KC, et al.","paperType":"guideline","findings":[],"whatItMeans":"The follicular and papillary thyroid cancer pages' recommendations for lobectomy, selective iodine and surveillance of microcarcinoma follow this guideline.","caveats":["Under revision; ESTIMABL2 and IoN have since supported omitting iodine in low-risk disease."],"changedPractice":true},"route":"/key-papers/paper-ata-2015-thyroid-nodules-dtc-haugen-thyroid-2016/","neighbours":{"cancer":[{"id":"follicular-thyroid-cancer","kind":"cancer","name":"Follicular thyroid cancer","route":"/cancers/follicular-thyroid-cancer/"},{"id":"papillary-thyroid-cancer","kind":"cancer","name":"Papillary thyroid cancer","route":"/cancers/papillary-thyroid-cancer/"}]}}