{"entity":{"id":"paper-boroni-atpbr-lancet-rha-2026","kind":"paper","name":"The Brazilian Population Tumor Atlas Project: addressing representation in cancer genomics in Brazil","aka":["Atlas Tumoral da População Brasileira","ATPBR"],"tldr":"Brazilian tumours are scarcely represented in the world's cancer genome databases, so the national cancer institute is building a public atlas of the molecular make-up of tumours from Brazilian patients.","summary":"This paper sets out the Brazilian Population Tumor Atlas (Atlas Tumoral da População Brasileira, ATPBR), run from Brazil's national cancer institute INCA. The authors argue that Brazil and other Latin American countries are underrepresented in global genomic research because of underfunding and infrastructure limits, which matters more in a genetically diverse population. ATPBR aims to map the molecular signatures of cancer in Brazilian patients and to provide a secure platform for storing and sharing multi-omics tumour data. INCA's announcement of the paper (13 March 2026) says the project was approved in 2023 with R$8.72 million over three years under the Genomas Brasil programme and is coordinated by João Paulo Viola and Mariana Boroni.","asOf":"2026-11-03","links":[{"label":"DOI: 10.1016/j.lana.2026.101397","url":"https://doi.org/10.1016/j.lana.2026.101397"},{"label":"INCA: INCA leads project that drives precision oncology in Brazil (13 March 2026)","url":"https://www.gov.br/inca/pt-br/assuntos/noticias/2026/inca-lidera-projeto-que-impulsiona-oncologia-de-precisao-no-brasil"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":["cgp"],"targets":[],"drugs":[],"companies":[],"institutions":["inca-brazil"],"pathways":[],"terms":["ngs"],"trials":[],"people":["mariana-boroni"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo country deep dive, Brazil (wave 2)","editedOn":"2026-11-03"},"journal":"The Lancet Regional Health - Americas","year":2026,"doi":"10.1016/j.lana.2026.101397","pmid":"41725643","authors":"Boroni M, Costa Conteville L, Ribeiro Pinto LF, Viola JPB","paperType":"review","findings":["ATPBR's primary objective is a secure platform for the storage and dissemination of multi-omics tumour data from Brazilian patients.","INCA states the project was approved in 2023 with R$8.72 million over three years under the Genomas Brasil programme."],"whatItMeans":"Targeted treatments and genetic risk tools are built mostly on tumours from people of European ancestry. A Brazilian atlas is a step towards knowing whether the same markers, frequencies and drug targets hold for Brazilian patients.","caveats":["A description of a project and its rationale, not a report of results; its abstract gives no counts of tumours sequenced, and OnCo did not read the full text."]},"route":"/key-papers/paper-boroni-atpbr-lancet-rha-2026/","neighbours":{"technology":[{"id":"cgp","kind":"technology","name":"Comprehensive genomic profiling","route":"/technologies/cgp/"}],"institution":[{"id":"inca-brazil","kind":"institution","name":"Instituto Nacional de Câncer (INCA)","route":"/institutions/inca-brazil/"}],"term":[{"id":"ngs","kind":"term","name":"Next-generation sequencing (NGS)","route":"/terms/ngs/"}],"person":[{"id":"mariana-boroni","kind":"person","name":"Mariana Boroni","route":"/people/mariana-boroni/"}]}}