{"entity":{"id":"paper-esmo-non-epithelial-ovarian-ray-coquard-ann-oncol-2018","kind":"paper","name":"Non-epithelial ovarian cancer: ESMO clinical practice guidelines","aka":[],"tldr":"The ESMO guideline on the rarer ovarian cancers, including granulosa cell and other sex cord-stromal tumours and germ cell tumours, sets out surgery, when chemotherapy is needed, fertility preservation and long-term follow-up.","summary":"Evidence-based guideline covering diagnosis, staging, surgical management including fertility-sparing surgery, adjuvant and recurrent-disease chemotherapy, hormonal therapy and follow-up for malignant germ cell tumours and sex cord-stromal tumours of the ovary.","asOf":"2026-09-17","links":[{"label":"Ann Oncol 2018","url":"https://doi.org/10.1093/annonc/mdy001"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/29697741/"}],"tags":[],"related":[],"cancers":["granulosa-cell-tumour"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["annals-of-oncology"],"dependsOn":[],"notes":[],"journal":"Annals of Oncology","year":2018,"doi":"10.1093/annonc/mdy001","pmid":"29697741","authors":"Ray-Coquard I, Morice P, Lorusso D, et al.","paperType":"guideline","findings":[],"whatItMeans":"The observation after complete surgery for stage I granulosa cell tumour, lifelong inhibin monitoring and endocrine or bevacizumab-based options at relapse follow this guideline.","caveats":["Evidence in sex cord-stromal tumours is largely retrospective."],"changedPractice":true},"route":"/key-papers/paper-esmo-non-epithelial-ovarian-ray-coquard-ann-oncol-2018/","neighbours":{"cancer":[{"id":"granulosa-cell-tumour","kind":"cancer","name":"Adult granulosa cell tumour of the ovary","route":"/cancers/granulosa-cell-tumour/"}],"journal":[{"id":"annals-of-oncology","kind":"journal","name":"Annals of Oncology","route":"/journals/annals-of-oncology/"}]}}