{"entity":{"id":"paper-gonda-precede-consortium-recommendations-gastroenterology-2021","kind":"paper","name":"Recommendations for a more organized and effective approach to the early detection of pancreatic cancer from the PRECEDE (Pancreatic Cancer Early Detection) consortium","aka":[],"tldr":"The PRECEDE consortium set out how the field should organise itself to detect pancreatic cancer early: shared enrolment criteria, a common data and biospecimen registry, and international collaboration rather than isolated single-centre cohorts.","summary":"The Pancreatic Cancer Early Detection consortium published recommendations for a more organised and effective approach to early detection of pancreatic cancer, covering the coordination of high-risk cohorts, standardised data collection and biospecimen banking across centres.","asOf":"2026-09-24","links":[{"label":"Gonda et al., Gastroenterology 2021: PRECEDE consortium recommendations for early detection","url":"https://doi.org/10.1053/j.gastro.2021.08.036"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/34454916/"}],"tags":[],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":["pancreatic-surveillance","liquid-biopsy"],"targets":[],"drugs":[],"companies":[],"institutions":["nyu-perlmutter"],"pathways":[],"terms":[],"trials":["precede"],"people":["diane-simeone"],"bottlenecks":[],"keyPapers":[],"journals":["gastroenterology"],"dependsOn":[],"notes":[],"journal":"Gastroenterology","year":2021,"doi":"10.1053/j.gastro.2021.08.036","pmid":"34454916","authors":"Gonda TA, Everett JN, Wallace M, Simeone DM, PRECEDE Consortium.","paperType":"guideline","findings":["A coordinated multi-centre structure for high-risk cohorts, data and biospecimens is proposed."],"whatItMeans":"PRECEDE is the infrastructure answer to CAPS's problem: no single centre can enrol enough high-risk people to validate an early detection test.","caveats":["Recommendations, not results; no abstract text is indexed for this record.","Outcomes from the consortium cohort are not yet published."],"changedPractice":false},"route":"/key-papers/paper-gonda-precede-consortium-recommendations-gastroenterology-2021/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"technology":[{"id":"pancreatic-surveillance","kind":"technology","name":"High-risk pancreatic surveillance (CAPS / PRECEDE)","route":"/technologies/pancreatic-surveillance/"},{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"}],"institution":[{"id":"nyu-perlmutter","kind":"institution","name":"Laura and Isaac Perlmutter Cancer Center at NYU Langone Health","route":"/institutions/nyu-perlmutter/"}],"trial":[{"id":"precede","kind":"trial","name":"PRECEDE","route":"/trials/precede/"}],"person":[{"id":"diane-simeone","kind":"person","name":"Diane M. Simeone","route":"/people/diane-simeone/"}],"journal":[{"id":"gastroenterology","kind":"journal","name":"Gastroenterology","route":"/journals/gastroenterology/"}]}}