{"entity":{"id":"paper-jochelson-radiology","kind":"paper","name":"Contrast-enhanced Mammography: State of the Art","aka":[],"tldr":"Paper cited by one technology page, indexed on Europe PMC as PubMed record 33650905 and published in Radiology; the citing page links this DOI, which is how the record was matched.","summary":"Contrast-enhanced mammography (CEM) has emerged as a viable alternative to contrast-enhanced breast MRI, and it may increase access to vascular imaging while reducing examination cost. Intravenous iodinated contrast materials are used in CEM to enhance the visualization of tumor neovascularity. After injection, imaging is performed with dual-energy digital mammography, which helps provide a low-energy image and a recombined or iodine image that depict enhancing lesions in the breast. CEM has been demonstrated to help improve accuracy compared with digital mammography and US in women with abnormal screening mammographic findings or symptoms of breast cancer. It has also been demonstrated to approach the accuracy of breast MRI in preoperative staging of patients with breast cancer and in monitoring response after neoadjuvant chemotherapy. There are early encouraging results from trials evaluating CEM in the screening of women who are at an increased risk of breast cancer. Although CEM is a promising tool, it slightly increases radiation dose and carries a small risk of adverse reactions to contrast materials. This review details the CEM technique, diagnostic and screening uses, and future applications, including artificial intelligence and radiomics.\n\nIndexed on Europe PMC as PubMed record 33650905 (DOI 10.1148/radiol.2021201948). Matched by DOI alone: one technology page cites this DOI among its external links (the pages are listed under Related), and this page was written so that the citation resolves inside OnCo. No figure has been checked by an editor.","asOf":"2026-09-22","links":[{"label":"Radiology 2021","url":"https://doi.org/10.1148/radiol.2021201948"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/33650905/"},{"label":"Europe PMC","url":"https://europepmc.org/article/MED/33650905"}],"tags":["europepmc-ingest"],"related":["contrast-enhanced-mammography"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["radiology"],"dependsOn":[],"notes":[],"journal":"Radiology","year":2021,"doi":"10.1148/radiol.2021201948","pmid":"33650905","authors":"Jochelson MS, Lobbes MBI","paperType":"review","findings":[],"whatItMeans":"One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.","caveats":["Matched to the citing OnCo records by DOI alone; the summary reproduces the Europe PMC abstract and no figure has been verified against the full paper."]},"route":"/key-papers/paper-jochelson-radiology/","neighbours":{"technology":[{"id":"contrast-enhanced-mammography","kind":"technology","name":"Contrast-enhanced mammography","route":"/technologies/contrast-enhanced-mammography/"}],"journal":[{"id":"radiology","kind":"journal","name":"Radiology","route":"/journals/radiology/"}]}}