{"entity":{"id":"paper-liu-hanoi-head-neck-incidence-trends-jco-go-2026","kind":"paper","name":"Thirty-Year Trends (1991-2020) in Head and Neck Cancer Incidence Rates: Hanoi Cancer Registry, Vietnam","aka":[],"tldr":"In the Hanoi Cancer Registry, head and neck cancer rates rose from 10.9 per 100,000 in 1991 to 1995 to 18.8 in 2006 to 2010 and fell to 11.8 in 2016 to 2020, with nasopharyngeal cancer giving way to oral cavity cancer in men.","summary":"The authors used ICD-10 coded data from the Hanoi Cancer Registry for 1991 to 2020, 19,589 head and neck cancers of which 74% were in men, with ratio-based imputation for changes in Hanoi's administrative boundaries, joinpoint regression and age-period-cohort models.\n\nThe age-standardised rate was 10.9 per 100,000 in 1991 to 1995, peaked at 18.8 in 2006 to 2010 and was 11.8 in 2016 to 2020. Nasopharyngeal and sinonasal cancers fell from 68% to 21% of male cases and from 59% to 36% of female cases, while oral cavity cancers rose as a share of cases in men.","asOf":"2026-11-04","links":[{"label":"JCO Global Oncology 2026","url":"https://doi.org/10.1200/go-26-00083"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/42525914/"}],"tags":[],"related":[],"cancers":["head-and-neck","nasopharyngeal"],"sections":[],"technologies":["cancer-registries-surveillance"],"targets":[],"drugs":[],"companies":[],"institutions":["k-hospital-hanoi"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"journal":"JCO Global Oncology","year":2026,"doi":"10.1200/go-26-00083","pmid":"42525914","authors":"Liu AW, Do HVM, Nguyen GH, Nguyen ND, Tran LH, et al.","paperType":"observational","findings":["Age-standardised incidence: 10.9 per 100,000 (1991 to 1995), 18.8 (2006 to 2010), 11.8 (2016 to 2020).","Men were 62.2% of cases in 1991 to 1995 and 79% in 2016 to 2020.","Nasopharyngeal and sinonasal cancers fell from 68% to 21% of male cases; the models show declining risk in cohorts born after 1950."],"whatItMeans":"Head and neck cancer in northern Viet Nam is shifting from nasopharyngeal towards oral cavity cancer and towards men, which bears on where prevention and early detection should aim.","caveats":["One city's registry.","Boundary changes in Hanoi required imputation, and the abstract does not separate the effect of changes in reporting."],"participants":19589},"route":"/key-papers/paper-liu-hanoi-head-neck-incidence-trends-jco-go-2026/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"nasopharyngeal","kind":"cancer","name":"Nasopharyngeal carcinoma","route":"/cancers/nasopharyngeal/"}],"technology":[{"id":"cancer-registries-surveillance","kind":"technology","name":"Cancer registries and population surveillance","route":"/technologies/cancer-registries-surveillance/"}],"institution":[{"id":"moh-vietnam","kind":"institution","name":"Ministry of Health, Viet Nam","route":"/institutions/moh-vietnam/"},{"id":"k-hospital-hanoi","kind":"institution","name":"Vietnam National Cancer Hospital (K Hospital)","route":"/institutions/k-hospital-hanoi/"}]}}