{"entity":{"id":"paper-psogi-pseudomyxoma-appendiceal-classification-am-j-surg-pathol-2016","kind":"paper","name":"PSOGI consensus for classification and pathological reporting of pseudomyxoma peritonei and associated appendiceal neoplasia","aka":[],"tldr":"Pathologists from around the world agreed on what to call the mucinous tumours of the appendix and the jelly-like peritoneal disease they cause, replacing a tangle of older names with low-grade appendiceal mucinous neoplasm, high-grade neoplasm and adenocarcinoma.","summary":"Modified Delphi consensus of the Peritoneal Surface Oncology Group International defining terminology for appendiceal mucinous neoplasms (low-grade appendiceal mucinous neoplasm or LAMN, high-grade appendiceal mucinous neoplasm, and mucinous adenocarcinoma with well, moderately or poorly differentiated grades, the last including signet ring cells) and for pseudomyxoma peritonei (acellular mucin, low-grade, high-grade, and high-grade with signet ring cells).\n\nThe scheme was adopted by the WHO 2019 digestive classification and underpins prognosis and the decision to offer cytoreductive surgery with HIPEC.","asOf":"2026-09-18","links":[{"label":"Am J Surg Pathol 2016","url":"https://doi.org/10.1097/PAS.0000000000000535"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/26492181/"}],"tags":[],"related":[],"cancers":["low-grade-appendiceal-mucinous-neoplasm","appendiceal-adenocarcinoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"journal":"American Journal of Surgical Pathology","year":2016,"doi":"10.1097/PAS.0000000000000535","pmid":"26492181","authors":"Carr NJ, Cecil TD, Mohamed F, et al.","paperType":"review","findings":[],"whatItMeans":"Whether an appendiceal tumour is called LAMN or adenocarcinoma, and whether peritoneal disease is graded low or high, decides prognosis and treatment; this paper set those names.","caveats":["Consensus of experts rather than outcome data.","Terms such as 'mucinous carcinoma peritonei' in older papers do not map cleanly onto the new grades."],"changedPractice":true},"route":"/key-papers/paper-psogi-pseudomyxoma-appendiceal-classification-am-j-surg-pathol-2016/","neighbours":{"cancer":[{"id":"appendiceal-adenocarcinoma","kind":"cancer","name":"Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell)","route":"/cancers/appendiceal-adenocarcinoma/"},{"id":"low-grade-appendiceal-mucinous-neoplasm","kind":"cancer","name":"Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei","route":"/cancers/low-grade-appendiceal-mucinous-neoplasm/"}]}}